Excell 22 Isotone Solution

Introduction Excell 22 Isotone Solution

The Excell 22 Isotone Solution produced by Labnovation is carefully calibrated to meet the pressure-sensor, impedance-counter, and electrical-conductivity requirements of the Excell 22 cell counter.

Ensuring the stability of blood cell membranes during sample transport through the analyzer's hydraulic circuits is vital for achieving accurate hematology results. Excell 22 Isotone Solution, a high-quality and reliable diluent produced by Labnovation and available in Iran through Arya Tashkhis Pars, is supplied in 20-liter containers. It is carefully calibrated to meet the pressure-sensor, impedance-counter, and electrical-conductivity requirements of the Excell 22 cell counter, facilitating precise blood dilution in pathology tests.

Strategic Applications and Osmotic Mechanism of Isotonic Solution (Diluent)

Within the instrument circuit, this diluent acts as the main sheath and carrier fluid, fulfilling these key roles:

• Precision Sample Dilution: Uniformly and accurately dilutes whole blood to reduce cellular concentration, enabling single-cell counting in the micron aperture without coincidence error.

• Absolute Preservation of Cell Membrane Osmotic Balance: Establishes a standard isotonic environment with osmotic pressure equal to that of the internal erythrocyte and platelet pressures; this mechanism prevents false swelling (lysis) or membrane shrinkage (crenation) during measurement.

• Providing System Ionized Conductivity (Background Conductivity): Stabilizes mineral-salt concentration to provide the electrical conductivity required by the electrical impedance method (Coulter Principle) for precise calculation of cell sizes and counts.

• Hydraulic Cleaning and Circuit Flushing: Continuously flushes the counting chamber walls and tubing between tests to eliminate carryover noise.

Technical Specifications and Device Compatibility

Quality Features and Operational Benefits of 20-Liter Containers

• Economical Configuration Ideal for High Workloads: The 20-liter volume extends reagent container changeover intervals, improving operator efficiency in high-throughput laboratories.

• Nano-Scale Particulate Filtration: Advanced micron filtration during production reduces background particle count to near zero, guaranteeing counting accuracy in the sensitive platelet (PLT) channel.

• Microorganism Growth Resistance: Uses a modern anti-fungal and anti-bacterial formulation free of biochemical interference to prevent algae or biofilm formation in the capillary paths of the Excell 22.33.

• Osmotic Factor Stability Down to the Last Drop: Fully ready-to-use structure with no risk of settling or changes in ionic concentration during storage.

Technical Limitations, Maintenance Tips, and Operational Interactions

To prevent calculation errors and cell chart shifts, it is essential to follow the following requirements:

• Storage Temperature Chain Adherence: Store the product strictly between 2 and 30°C and protect it from direct light. Freezing disrupts ionic balance and osmotic equilibrium, causing severe fluctuations in MCV (mean corpuscular volume) and HCT (hematocrit) upon thawing.

• Preventing Environmental Contamination Ingress: Avoid touching the suction probe or placing it on contaminated surfaces during container replacement; lint or dust ingress disrupts background counting.

• Controlling Hermetic Nozzle Connections: Due to extended use of the 20-liter container, ensure the cap and nozzle connector are tightly sealed to prevent liquid-phase evaporation and salt buildup.

Laboratory Staff FAQ

1. Why does uncalibrated osmotic pressure in non-standard diluents alter red blood cell indices?
   If the solution's osmotic pressure differs from the cell's (hypertonic or hypotonic), water moves in or out of the cell, causing erythrocytes to swell or shrink artificially. This structural change leads to inaccuracies in parameters such as MCV, HCT, and RDW. The Labnovation solution addresses this problem with high osmotic stability.

2. What is the hydraulic indicator of particle contamination or a damaged Isotone container?
   If the cell counter reports a high-particle-count error in the RBC or PLT channels during the initial background check, it indicates noise or unwanted particles in the diluent, so the container should be replaced.

3. Do severe ambient temperature fluctuations in the laboratory affect Isotone performance?
   Yes; significant variations in ambient temperature can affect liquid viscosity and hydroforming speed. To ensure stable instrument calibration, avoid placing the container near direct heating or cooling vents.

Price Inquiry and Purchasing Labnovation Excell 22 Isotone Solution

Protecting electronic boards and micron apertures in Excell cell counters requires the use of uniform, properly calibrated reagents. To purchase Excell 22 Isotone Solution in 20-liter containers or to inquire about hematology consumables pricing, visit the Padina Vista portal or contact our sales team. This product is backed by an assured formulation authenticity, an official expiration date, and authorization from the Arya Tashkhis Pars distribution network.

Technical Specifications محلول ایزوتون 22 Excell

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