Sysmex Lyser Solution

Introduction Sysmex Lyser Solution

The Sysmex Lysing Solution, produced by Labnovation is a specialized hematology reagent imported and distributed by Arya Tashkhis Pars.

Achieving the highest level of accuracy and reproducibility in 3-part (3-Part) cell counter hematology analysis depends directly on the biochemical stability and homogeneous performance of lytic reagents. Sysmex Lysing Solution, produced by the pioneering company Labnovation, is a calibrated and specialized hematology reagent imported and distributed across the Iranian diagnostic market by Arya Tashkhis Pars. Formulated in a dedicated 500 mL volume, this product offers complete hydraulic, physicochemical, and osmotic compatibility with the popular and widely used Sysmex KX21 and KX21N models to reconstruct precise results in leukocyte and hemoglobin measurements.

Strategic Applications and Biochemical Mechanism of Sysmex KX21 Lyse Solution

Calibrated injection of this reagent into the cell counter measuring chamber activates the following vital chain processes and biochemical reactions in whole blood samples:

• Rapid and Controlled Erythrocyte Membrane Lysis (RBC Lysis): Selectively and completely destroys red blood cells to physically remove them from the counting phase, without damaging or altering white blood cell (WBC) membrane or cytoplasmic structures.

• Facilitating 3-Part White Blood Cell Differential Counting (WBC 3-Part Differentiation): Optimally prepares and dimensionally stabilizes leukocytes for differentiating and counting the three primary cell populations (lymphocytes, neutrophils, and mixed cells) matching KX-series calculation algorithms.

• Photometric Hemoglobin Measurement and Release (Cyanide-Free HGB): Homogenizes released hemoglobin from erythrocytes and converts it into a stable color complex for accurate concentration readings in the photometric system without precipitate formation.

• Low Background Noise: The filtered formulation of this lyse eliminates background errors, preventing micron aperture blockage or noise generation during instrument background checks.

Technical Specifications and Device Compatibility

Quality Features and Operational Benefits of 500 mL Bottles

• Optimal Volume and Reduced Reagent Aging Risk: The 500 mL volume is designed to match medium-workload laboratories and KX-series aspiration rates, preventing reagent waste or premature product expiration.

• Safe, Cyanide-Free Formulation: Free of hazardous cyanide-based compounds, enhancing laboratory staff safety while reducing biological waste clearance and disposal challenges and costs.

• Hydraulic Compatibility with Sysmex Injection Pumps: Calibrated surface tension and viscosity avoid adding extra hydraulic load to device magnets and pumps, minimizing internal component wear.

• Fully Ready-to-Use Structure: Requires no dilution or secondary mixing, completely neutralizing environmental or cross-contamination risks.

Technical Limitations, Maintenance Tips, and Operational Interactions

To prevent blood parameter shifts and histogram fluctuations, adhering to the following technical requirements is mandatory:

• Storage Temperature Chain Management: Store this reagent strictly between 2 and 30°C, away from direct sunlight. Freezing degrades active lytic compound structures, resulting in incomplete lysis and falsely elevated WBC counts.

• Preventing Evaporative Concentration and Crystallization: Leaving bottle caps open for extended periods alters solution osmolality and precipitates mineral salts. Over time, these micro-crystals obstruct delicate chamber pathways and aspirating needles.

• Suction Probe Hygiene Protocols: Avoid touching suction probes or needles with bare hands or unsterile wipes during bottle replacement; cross-contamination disrupts background counts.

Laboratory Staff FAQ

1. Why does incomplete RBC lysis caused by non-standard lyse reagents disrupt CBC test results?
   If erythrocyte membranes are not completely destroyed, remaining membrane fragments (RBC Ghosts) are evaluated as small leukocytes or large platelets in the counting chamber. This biochemical interference falsely inflates WBC parameters and distorts cellular histograms. Labnovation solution provides complete stability in removing this interference.

2. What are the clear signs of expired or degraded Sysmex Lysing Solution?
   Cloudy liquid color, powdery deposits at the bottom of the bottle, persistently abnormal background counts in WBC and HGB channels, and hydraulic stability errors flagged by the analyzer software indicate reagent degradation.

3. What is the role of lyse solution in measuring Hemoglobin (HGB) parameters?
   After lysing erythrocyte membranes, this solution releases cytoplasmic hemoglobin and forms molecular bonds with it. The resulting stable color complex is measured by the cell counter photometer at a specific wavelength to determine precise hemoglobin concentrations.

Price Inquiry and Purchasing Labnovation Sysmex Lysing Solution

Guaranteeing diagnostic index reproducibility and protecting the hydraulic systems of Sysmex analyzers rely on sourcing calibrated reagents. To buy Sysmex Lysing Solution in a 500 mL volume and inquire about hematology reagent pricing, visit the specialized Padina Vista portal or contact our sales department. Supplied with guaranteed technical authenticity, valid expiration dates, and official authorization from Arya Tashkhis Pars.

Technical Specifications محلول لایزر Sysmex

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